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BioXclude Handling
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Sinus Augmentation / Perforation Handling Guide
Step-by-step handling instructions for BioXclude® dehydrated human deepithelialized amnion-chorion membrane (ddACM)
Schneiderian Membrane Repair With BioXclude
Use of BioXclude to repair sinus perforations is simple fast and effective. Working as a self adhering "patch" without the need for fixation, deepithelialized amnion-chorion allograft (Bioxclude) provides an effective solution to Schneiderian membrane repair.

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The osteogenic potential of the maxillary sinus Schneiderian membrane was further explored in a recent publication by Drs. Insua, Monje, Urban, et al. Their findings support the rationale for perforation repair using BioXclude, a membrane which contributes to healing. The active signaling proteins within BioXclude support angiogensis and act as a stem cell "magnet" recruiting the body's own mesenchymal stem cells to the site.




Minimially Invasive Crestal Sinus Lift
  • Perfect application for 12 x 12 mm size.
  • Easily applied with an osteotome for repair or reinforcement.
  • An additional BioXclude may be placed and left intentionally exposed over the immediate implant to expand zone and quality of keratinized tissue



Lateral Window Approach
For a lateral window approach a 20 x 30 mm size can be cut in half allowing for two 15 x 20 mm pieces: (1) piece to repair or reinforce the sinus membrane, and (1) a second piece to cover the lateral access window.

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Proven Clinical Efficacy With BioXclude
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The pre-operative CBCT reveals only 2 - 3 mm of native crestal bone. Schneiderian membrane perforation occurs during sinus augmentation. A dry BioXclude is placed on the perforation to repair, tightly sealing it once hydrated. Particulate bone is then packed into the sinus cavity.

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Holtzclaw, D. J Perio 2015; 86 (8): 936-940
Sinus Total
Augmentations
Implants
Placed
Implants
Failed
Perforated 9 23 1
Non-Perforated 95 158 3
All Augmentations allowed for Successful Restoration!

Holtzclaw, D. J Perio 2015; 86 (8): 936-940
Sinus Total
Augmentations
Implants
Placed
Implants
Failed
Perforated 9 23 1
Non-Perforated 95 158 3
All Augmentations allowed for Successful Restoration!

An additional BioXclude membrane is placed over the bone graft, covering the lateral window. Adequate bone is achieved at 5 months with implants placed and immediately loaded with a transitional prosthesis.