There are two reasons:

(1) Is simple mechanical disruption. When a patient is told to "rinse" with a product, they tend to do so more vigorously. All rinsing/swishing/spitting should be avoided for 3 days post-operatively; followed by tap water rinses only for the following 7 days post-operatvely.

(2) In general, the use of Cholorhexidine post-surgically has decreased due to literature indicating that it inhibits fibroblast activity. Specifically, regarding use wth BioXclude, the issue is that Chlorhexidine's cationic nature causes it it bind with the proteins in BioXclude.

Remember BioXclude is inherently antibacterial, and therefore decreases concern experienced with other exposed materials.

This requires a full examination and is ultimately determined by the clinician. However if the patient is not demonstrating any typical signs of infection, (i.e., fever, erythema, purulence, etc.), and the sole concern is the membrane appearance, please note that BioXclude can have a "milky", opaque appearance in some patients post-operatively when left exposed. This seems more prevalent in smokers and slow healing patients; however, this is still considered a "normal" healing appearance.

BioXclude can sometimes appear translucent post-operatvely. If you can see particulate bone graft, but there is not substantial sequestered graft material, your membrane is likely intact, as demonstrated in this 4 day post-op patient:

If graft material is lost, see suturing technique recommendations, as that is a common culprit.