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BioXclude Handling

Non-Surgical Periodontal Therapy Adjunct Handling Guide
Step-by-step handling instructions for BioXclude® dehydrated human deepithelialized amnion-chorion membrane (ddACM)
Handling Guide

BioXclude is intended for use after standard root planing and scaling procedures (ScRP), for periodontal pocket depths ≤ 5 mm. Clinicians generally have an algorithm related to when they choose to employ a locally applied non-surgical scaling and root planing adjunct.

The following protocol belongs to Mark Lucas, DDS, MS, and has been utilized for initial trials. The protocol reserves said therapies for periodontal defects which presented at the phase 1 periodontal reevaluation appointment as significantly improved but not quite into the predictably maintainable zone of ≤ 4mm. Also, periodontal maintenance patients exhibiting some site-specific breakdown could be candidates for local ScRP and locally applied adjunct.

Non-surgical periodontal therapy adjunct recommended dose size: 8x8 mm per site

Post-Operative Instructions
  • No eating or drinking for 30 minutes following treatment.
  • Avoid touching the treated areas.
  • Wait 12 hours after your treatment before brushing teeth.
  • Wait 10 days before using floss, toothpicks, or other devices designed to clean between the treated teeth.
  • Avoid foods for 1 week that could hurt your gums (popcorn, chips).
  • Don't chew gum or eat sticky foods.
After 10 days, resume cleaning between the treated teeth on a daily basis.

Handling Instructions
Perform standard
scaling and root planing

Pressure gauze to
decrease bleeding from treated site

Use BioXclude in 3 Simple Steps
  • Pick up the dry membrane with dry forceps and hydrate it by immersing in sterile saline or sterile water until the membrane is pliable (Approximately 30 seconds)
  • Wetted membrane is initially introduced to the pocket with cotton forceps and the other instrument (probe or cord packer) is used to drive the membrane into the pocket
  • Exchange the forceps for a second cord packer or probe
  • Alternate one instrument to stabilize the membrane while the other instrument drives it into the pocket, continue until the membrane is condensed to the bottom of the pocket