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Category: Research

New BioXclude Publication - Sandwich Technique for Enhanced Periodontal Regenerative Therapy

BioXclude is by far the most versatile regenerative material available, often described as Mother Nature’s duct tape. Providing customers with a means to reduce material costs and simplify inventory. To emphasize these benefits, I am pleased to share a new BioXclude article recently published in Clinical Advances in Periodontics.

New BioXclude Publication (Click to View)

The publication demonstrates for the first-time, placement of BioXclude onto prepared root surfaces prior to guided tissue regeneration.



BioXclude is by far the most versatile regenerative material available, often described as Mother Nature’s duct tape. Providing customers with a means to reduce material costs and simplify inventory. To emphasize these benefits, I am pleased to share a new BioXclude article recently published in Clinical Advances in Periodontics.

New BioXclude Publication (Click to View)

The publication demonstrates for the first-time, placement of BioXclude onto prepared root surfaces prior to guided tissue regeneration.

Courtesy of Yusuke Hamada, DDS, MSD, Indiana University, Department of Periodontics
1. Initial Appointment (#5 & 30)
2. Pre-op Radiograph (#5 & #30)
3. Post debridement (#5)
4. BioXclude Applied to Root Surface (#5)
5. FDBA in place (#5)
6. BioXclude over the FDBA (#5)
7. Post debridement (#30)
8. BioXclude applied to root surface (#30)
9. FDBA in place (#30)
10. BioXclude over the FDBA (#30)
11. 6 month post-op (#5 & #30)
12. 6 Month post-op radiograph (#5 & #30)


Courtesy of Yusuke Hamada, DDS, MSD, Indiana University, Department of Periodontics
1. Initial Appointment (#5 & 30)
2. Pre-op Radiograph (#5 & #30)
3. Post debridement (#5)
4. BioXclude Applied to Root Surface (#5)
5. FDBA in place (#5)
6. BioXclude over the FDBA (#5)
7. Post debridement (#30)
8. BioXclude applied to root surface (#30)
9. FDBA in place (#30)
10. BioXclude over the FDBA (#30)
11. 6 month post-op (#5 & #30)
12. 6 Month post-op radiograph (#5 & #30)
I recognize that this is only case report level documentation. Fortunately, and with great pride, I am pleased to inform you that Snoasis Medical is sponsoring a human clinical histologic evaluation to demonstrate using BioXclude over prepared roots results in periodontal regeneration i.e., new bone, periodontal ligament, and cementum.
Attending ISPRD 2020 in Boston, MA? Dr. Yusuke Hamada, DDS, MSD & Dr. Muneiko Ro, DDS, PhD will be presenting on this novel approach for periodontal regenerative therapy. To learn more about this approach to better save failing teeth, and more generally, how adoption of BioXclude is true a practice game changer. I encourage you to attend the 14th ISPRD meeting in Boston MA, June 9-12, 2022. Snoasis Medical is the main sponsor and at this meeting histologic results using BioXclude for periodontal regeneration will be presented for the first time. Click to Register.
I want to publicly acknowledge and congratulate lead author Dr. Yusuke Hamada (Indiana University, Department of Periodontics) for pioneering this novel regenerative approach and for allowing me to share this case with you today.
Warm Regards,
Snoasis Medical

Robert Tofe
President and Founder