Category: Research
NEW BioXclude® Publication Demonstrates Antibacterial Properties of Membrane
Today, I am pleased to share our second publication documenting the antibacterial properties of our Purion® processed human deepithelialized amnion-chorion membrane (BioXclude®). In this study, appearing in the prestigious journal Scientific Reports (4.6 Impact Factor), Palanker, et al., reveals that BioXclude possesses “extremely high anti-microbial efficacy against oral Streptococci”. Click to View.
Today, I am pleased to share our second publication documenting the antibacterial properties of our Purion® processed human deepithelialized amnion-chorion membrane (BioXclude®). In this study, appearing in the prestigious journal Scientific Reports (4.6 Impact Factor), Palanker, et al., reveals that BioXclude possesses “extremely high anti-microbial efficacy against oral Streptococci”. Click to View.
BioXclude Possesses "Extremely High Anti-Microbial Efficacy Against Oral Streptococci."
Using three different antimicrobial assays, (A) an insert assay, (B) an agar contact assay, (C) and a glass-bottom well assay, BioXclude proved to have potent antimicrobial properties against Streptococcus gordonii, especially when compared to control membranes of porcine pericardium collagen, which showed no antimicrobial activity. Bacterial vitality was measured by using confocal fluorescent microscopy at 8, 24, and 48 hours.
Using three different antimicrobial assays, (A) an insert assay, (B) an agar contact assay, (C) and a glass-bottom well assay, BioXclude proved to have potent antimicrobial properties against Streptococcus gordonii, especially when compared to control membranes of porcine pericardium collagen, which showed no antimicrobial activity. Bacterial vitality was measured by using confocal fluorescent microscopy at 8, 24, and 48 hours.
Bacteria Did Not Grow on BioXclude
This new publication is a must-read if you love good science and research. As these figures clearly demonstrate, S.gordonii flourished on collagen but not on BioXclude.
Streptococcus grodonii grown on BioXclude vs Collagen
Streptococcus grodonii grown on BioXclude vs Collagen
Of note, this study employed a novel assay to measure antimicrobial potency. In my opinion, this in vitro model is a powerful tool to measure the retention of “biologic potential” following tissue processing and clearly shows the value of BioXclude’s patented Purion® process.
Antibacterial Benefit Only Provided by BioXclude
I'm not a scientist, nor am I a clinician, but there is one thing I can say for sure: having a barrier membrane that possesses antibacterial properties is a very positive and important characteristic, a benefit only provided by our Purion® processed BioXclude!
I want to thank Dr. Nathan Palanker for conducting this exciting research and express my sincere appreciation for Dr. Bing Yan Wang and the periodontal program at Texas Health Sciences Center at Houston for providing technically valid data on our Purion® processed BioXclude to our customers.
I'm not a scientist, nor am I a clinician, but there is one thing I can say for sure: having a barrier membrane that possesses antibacterial properties is a very positive and important characteristic, a benefit only provided by our Purion® processed BioXclude!
I want to thank Dr. Nathan Palanker for conducting this exciting research and express my sincere appreciation for Dr. Bing Yan Wang and the periodontal program at Texas Health Sciences Center at Houston for providing technically valid data on our Purion® processed BioXclude to our customers.
Warm Regards,
Snoasis Medical
Robert Tofe
President & Founder
Snoasis Medical
Robert Tofe
President & Founder