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IJPRD Publication Highlights the Benefits of BioXclude in Challenging Peri-Implantitis Case



Vinay Bhide
DDS, MSc
BioXclude is the most versatile regenerative material in dentistry. By providing both an occlusive barrier and inherent biological factors that are known to play an important role in wound healing, BioXclude can provide significant clinical advantages over traditional barrier membranes. To emphasize these benefits, I am pleased to share a BioXclude article published in The International Journal of Periodontics & Restorative Dentistry (IJPRD) by Dr. Vinay Bhide, DDS, MSc (Aurora, ON, Canada). Click here for the full publication.

As you will see, this was a very challenging case with a successful outcome. In the publication, Dr. Bhide concludes, “While thorough defect debridement and meticulous implant surface decontamination with the titanium brush, used in combination with the chemical elements described above, were undoubtedly important for the successful results in the present case, it is likely that the choice of barrier membrane was also a critical factor, given the severity of the bony defect. For these reasons, BioXclude was selected for its unique physical and biologic properties, thus making it an attractive alternative to the traditionally used collagen-based membranes.”



Vinay Bhide
DDS, MSc

BioXclude is the most versatile regenerative material in dentistry. By providing both an occlusive barrier and inherent biological factors that are known to play an important role in wound healing, BioXclude can provide significant clinical advantages over traditional barrier membranes. To emphasize these benefits, I am pleased to share a BioXclude article published in The International Journal of Periodontics & Restorative Dentistry (IJPRD) by Dr. Vinay Bhide, DDS, MSc (Aurora, ON, Canada). Click here for the full publication.

As you will see, this was a very challenging case with a successful outcome. In the publication, Dr. Bhide concludes, “While thorough defect debridement and meticulous implant surface decontamination with the titanium brush, used in combination with the chemical elements described above, were undoubtedly important for the successful results in the present case, it is likely that the choice of barrier membrane was also a critical factor, given the severity of the bony defect. For these reasons, BioXclude was selected for its unique physical and biologic properties, thus making it an attractive alternative to the traditionally used collagen-based membranes.”
Courtesy of Vinay Bhide, DDS, MSc, Aurora, ON, Canada
1. Flap elevation reveals significant peri-implant bone loss.
2. Titanium brush used to carefully cleanse & detoxify the exposed implant surface after gentle rinsing with 3% hydrogen peroxide solution.
3. Implant after debridement of granulation tissue and implant surface decontamination.
4. Minocycline microspheres were added to the reconstituted NBBM particulate graft.
5. Bony defect was carefully grafted with NBBM particulate graft material.
6. BioXclude applied over the grafted area.
7. BioXclude adapted to the site, sealing it from surrounding tissues.
8. Tension-free primary closure.
9. 1 year postoperative CBCT shows reestablishment of a buccal bone shelf in the area where bone was previously lost due to peri-implantitis.
10. 2 year postoperative CBCT shows maintenance of the buccal bone contour and further consolidation of the bone graft.


Courtesy of Vinay Bhide, DDS, MSc, Aurora, ON, Canada
1. Flap elevation reveals significant peri-implant bone loss.
2. Titanium brush used to carefully cleanse & detoxify the exposed implant surface after gentle rinsing with 3% hydrogen peroxide solution.
3. Implant after debridement of granulation tissue and implant surface decontamination.
4. Minocycline microspheres were added to the reconstituted NBBM particulate graft.
5. Bony defect was carefully grafted with NBBM particulate graft material.
6. BioXclude applied over the grafted area.
7. BioXclude adapted to the site, sealing it from surrounding tissues.
8. Tension-free primary closure.
9. 1 year postoperative CBCT shows reestablishment of a buccal bone shelf in the area where bone was previously lost due to peri-implantitis.
10. 2 year postoperative CBCT shows maintenance of the buccal bone contour and further consolidation of the bone graft.
I would like to publicly acknowledge the lead author, Dr. Vinay Bhide, for his continued support and documentation.
Warm Regards,
Snoasis Medical

Matt Burns
Director of Business Development